OA in younger populations is more commonly associated with traumatic injuries or sports practices. OA is the third-largest contributor to the years lived with disability among musculoskeletal disorders, accounting for around 7.1% of this burden. OA is a slow, progressive and debilitating with a high prevalence in the active adult population, increasing worldwide. Osteoarthritis (OA) is a multifactorial disease that leads to articular cartilage degradation, affecting all joint components. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material.
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